Health & Medical Question

(Section numbering is consistent with numbering in Final Project prompt.)

1. Human Health Risk AssessmentPart 2
   You will continue to evaluate the health risk of this environmental hazard (Lead) by examining its dose-response and exposure risks.
   1. Hazard Identification. Please continue using the Human Health Risk Assessment Template as you complete Part A: Hazard Identification. Hazard identification is the process of identifying and selecting environmental agent(s) and health effect(s) for assessment. In this step, the main question addressed is this: Does this agent have adverse effects? To answer this question, please review the literature for information on the following:
      • Explain relevant toxicokinetics, including the absorption/uptake, distribution, metabolism, and elimination processes. Provide a summary (one to two sentences) for each process.
      • Discuss relevant toxicodynamics. Summarize the following:
        • The effects on the human body (one to three sentences);
        • The mechanisms that impact human health (one to three sentences);
        • The insights into the possible effects (if known) (one to two sentences).
      • Depict the Mode of Action by creating a concept map and inserting this image into the template. Your concept map will serve as a testable model of environmental insult. You may find it helpful to review (reference this resource as necessary) while constructing the concept map. In your concept map, illustrate the sequence of key events and processes, as follows:
        • Start with interaction of an agent and a cell,
        • Proceed through to the operational and anatomical changes, and
        • Conclude with the resulting adverse effects on human health.
   2. Dose-Response. Please continue using the Human Health Risk Assessment Template as you complete Part B: Dose-Response. When public health professionals assess the dose-response, the relationship between exposure and effects is examined, answering the question: What are the health problems at different exposures? In the field, this assessment would involve significant data collection and processing. However, for this assignment, you will summarize the dose-response given readily available information. Using the Human Health Risk Assessment Template, address the following:
      • Adverse Effects (these might include physical, mental, socioeconomic, psychosocial, or other effects). Summarize the adverse effects at different dose levels (dose-responses). Please refer to the for further explanation on these components.
   3. Exposure. Please continue using the Human Health Risk Assessment Template as you complete Part C: Exposure.” When public health professionals assess the exposure, the estimation or measurement of the magnitude, duration, and timing of human exposure to the agent of concern is a main focus. In this field, the main questions addressed by this type of assessment includes: (1) How much of the pollutant are people exposed to during a specific time period? or (2) How many people are exposed? In the field, this assessment would involve significant data collection and processing. However, for this assignment, you will summarize the exposure given readily available information. Using the Human Health Risk Assessment Template, address the following:
      • Exposure pathway and exposure route. Identify the chemicals exposure pathway and route. Please refer to the for further explanation on these components.

What to Submit

Utilize and submit the Milestone Two section of the Human Health Risk Assessment Template (linked in Module Three of your online course). I have attached the document below along with Milestone Section One

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